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Tumor Necrosis Factor Receptor 2 Restricts the Pathogenicity of CD8(+) T Cells in Mice with Colitis

BACKGROUND & AIMS: Tumor necrosis factor (TNF) receptor 2 (TNFR2, Tnfrsf1b) regulates multiple aspects of immune function; but little is known about its role in the immunopathogenesis of inflammatory bowel disease (IBD). We investigated whether TNFR2 restricts the activity of specific immune cel...

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Pubblicato in:Gastroenterology
Autori principali: Punit, Shivesh, Dubé, Philip E., Liu, Cambrian Y., Girish, Nandini, Washington, M. Kay, Polk, D. Brent
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841683/
https://ncbi.nlm.nih.gov/pubmed/26072395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2015.06.004
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