Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA

Neisseria adhesin A (NadA) is present on the meningococcal surface and contributes to adhesion to and invasion of human cells. NadA is also one of three recombinant antigens in the recently-approved Bexsero vaccine, which protects against serogroup B meningococcus. The amount of NadA on the bacteria...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Liguori, Alessia, Malito, Enrico, Lo Surdo, Paola, Fagnocchi, Luca, Cantini, Francesca, Haag, Andreas F., Brier, Sébastien, Pizza, Mariagrazia, Delany, Isabel, Bottomley, Matthew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841544/
https://ncbi.nlm.nih.gov/pubmed/27105075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005557
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