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Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats

Sympathetic vasomotor tone is elevated in obesity-related hypertension. Orexin importantly regulates energy metabolism and autonomic function. We hypothesized that alteration of orexin receptor in the paraventricular nucleus (PVN) of the hypothalamus leads to elevated sympathetic vasomotor tone in o...

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Publicat a:Neuropharmacology
Autors principals: Zhou, Jing-Jing, Yuan, Fang, Zhang, Yi, Li, De-Pei
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841448/
https://ncbi.nlm.nih.gov/pubmed/26277341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.08.012
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