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Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats

Sympathetic vasomotor tone is elevated in obesity-related hypertension. Orexin importantly regulates energy metabolism and autonomic function. We hypothesized that alteration of orexin receptor in the paraventricular nucleus (PVN) of the hypothalamus leads to elevated sympathetic vasomotor tone in o...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Zhou, Jing-Jing, Yuan, Fang, Zhang, Yi, Li, De-Pei
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841448/
https://ncbi.nlm.nih.gov/pubmed/26277341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.08.012
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