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Adenoviral Gene Therapy for Diabetic Keratopathy: Effects on Wound Healing and Stem Cell Marker Expression in Human Organ-cultured Corneas and Limbal Epithelial Cells

The goal of this protocol is to describe molecular alterations in human diabetic corneas and demonstrate how they can be alleviated by adenoviral gene therapy in organ-cultured corneas. The diabetic corneal disease is a complication of diabetes with frequent abnormalities of corneal nerves and epith...

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Библиографические подробности
Опубликовано в: :J Vis Exp
Главные авторы: Kramerov, Andrei A., Saghizadeh, Mehrnoosh, Ljubimov, Alexander V.
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841362/
https://ncbi.nlm.nih.gov/pubmed/27077448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54058
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