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Normalization of Wound Healing and Diabetic Markers in Organ Cultured Human Diabetic Corneas by Adenoviral Delivery of c-Met Gene

PURPOSE. Diabetic corneas display altered basement membrane and integrin markers, increased expression of proteinases, decreased hepatocyte growth factor (HGF) receptor, c-met proto-oncogene, and impaired wound healing. Recombinant adenovirus (rAV)–driven c-met overexpression in human organ-cultured...

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Hlavní autoři: Saghizadeh, Mehrnoosh, Kramerov, Andrei A., Yu, Fu-shin X., Castro, Maria G., Ljubimov, Alexander V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Association for Research in Vision and Ophthalmology, Inc. 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846188/
https://ncbi.nlm.nih.gov/pubmed/19933191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4569
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