Protective Effect of Tempol on Acute Kidney Injury Through PI3K/Akt/Nrf2 Signaling Pathway

BACKGROUND/AIMS: Tempol is a protective antioxidant against ischemic injury in many animal models. The molecular mechanisms are not well understood. Nuclear factor erythroid 2-related factor (Nrf2) is a master transcription factor during oxidative stress, which is enhanced by activation of protein k...

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Publicado en:Kidney Blood Press Res
Autores principales: Zhang, Gensheng, Wang, Qiaoling, Zhou, Qin, Wang, Renjun, Xu, Minze, Wang, Huiping, Wang, Lei, Wilcox, Christopher S., Liu, Ruisheng, Lai, En Yin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841277/
https://ncbi.nlm.nih.gov/pubmed/26894882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000443414
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