Validation of a High-Throughput Screening Assay for Identification of Adjunctive and Directly Acting Antimicrobials Targeting Carbapenem-Resistant Enterobacteriaceae

We describe development and validation of a high-throughput screen (HTS) for identifying small molecules that restore the efficacy of carbapenems (adjunctives) and/or directly inhibit growth of carbapenem-resistant Enterobacteriaceae (CRE). Our HTS assay is based on a screen–counterscreen approach u...

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Vydáno v:Assay Drug Dev Technol
Hlavní autoři: Smith, Kenneth P., Kirby, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2016
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4841070/
https://ncbi.nlm.nih.gov/pubmed/27045615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2016.701
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