Development of a central nervous system axonal myelination assay for high throughput screening

BACKGROUND: Regeneration of new myelin is impaired in persistent multiple sclerosis (MS) lesions, leaving neurons unable to function properly and subject to further degeneration. Current MS therapies attempt to ameliorate autoimmune-mediated demyelination, but none directly promote the regeneration...

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Détails bibliographiques
Publié dans:BMC Neurosci
Auteurs principaux: Lariosa-Willingham, Karen D., Rosler, Elen S., Tung, Jay S., Dugas, Jason C., Collins, Tassie L., Leonoudakis, Dmitri
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Methodology Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840960/
https://ncbi.nlm.nih.gov/pubmed/27103572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0250-2
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