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The T-box transcription factor TBX3 drives proliferation by direct repression of the p21(WAF1) cyclin-dependent kinase inhibitor

BACKGROUND: TBX3, a member of the T-box family of transcription factors, is essential in development and has emerged as an important player in the oncogenic process. TBX3 is overexpressed in several cancers and has been shown to contribute directly to tumour formation, migration and invasion. Howeve...

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Detalhes bibliográficos
Publicado no:Cell Div
Main Authors: Willmer, Tarryn, Hare, Shannagh, Peres, Jade, Prince, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840944/
https://ncbi.nlm.nih.gov/pubmed/27110270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13008-016-0019-0
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