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The T-box transcription factor TBX3 drives proliferation by direct repression of the p21(WAF1) cyclin-dependent kinase inhibitor

BACKGROUND: TBX3, a member of the T-box family of transcription factors, is essential in development and has emerged as an important player in the oncogenic process. TBX3 is overexpressed in several cancers and has been shown to contribute directly to tumour formation, migration and invasion. Howeve...

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Bibliografische gegevens
Gepubliceerd in:Cell Div
Hoofdauteurs: Willmer, Tarryn, Hare, Shannagh, Peres, Jade, Prince, Sharon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840944/
https://ncbi.nlm.nih.gov/pubmed/27110270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13008-016-0019-0
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