CXCR4 inhibitor attenuates ovalbumin-induced airway inflammation and hyperresponsiveness by inhibiting Th17 and Tc17 cell immune response

Accumulating evidence suggests that chemokine (C-X-C motif) ligand 12 (CXCL12) and its receptor chemokine (C-X-C motif) receptor 4 (CXCR4) may contribute to the pathogenesis of allergic asthma. However, the underlying molecular mechanisms remain to be fully understood. T-helper 17 cells (Th17) and T...

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Publicado no:Exp Ther Med
Main Authors: CHEN, HUILONG, XU, XIANGQIN, TENG, JIEMING, CHENG, SHENG, BUNJHOO, HANSVIN, CAO, YONG, LIU, JIN, XIE, JUNGANG, WANG, CONGYI, XU, YONGJIAN, XIONG, WEINING
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840799/
https://ncbi.nlm.nih.gov/pubmed/27168818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3141
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