CXCR4 inhibitor attenuates allergen-induced lung inflammation by down-regulating MMP-9 and ERK1/2

Chemokine (C-X-C motif) ligand 12 (CXCL12) and its receptor chemokine receptor 4 (CXCR4) have been recognized to play a crucial role in the pathogenesis of bronchial asthma, but the underlying molecular mechanisms are yet to be fully addressed. In the present report we demonstrated that CXCL12/CXCR4...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Chen, Huilong, Xu, Xiangqin, Teng, Jieming, Cheng, Sheng, Bunjhoo, Hansvin, Cao, Yong, Liu, Jin, Xie, Jungang, Wang, Congyi, Xu, Yongjian, Xiong, Weining
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525886/
https://ncbi.nlm.nih.gov/pubmed/26261552
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