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Imperatorin derivative OW1 inhibits the upregulation of TGF-β and MMP-2 in renovascular hypertension-induced cardiac remodeling

Chronic hypertension induces vascular and cardiac remodeling. OW1 is a novel imperatorin derivative that was previously reported to inhibit vascular remodeling and improve kidney function affected by hypertension. In the present study, the effect of OW1 on the cardiac remodeling induced by hypertens...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: ZHOU, NAN, ZHU, YANING, ZHANG, PENG, ZHANG, YU, ZHOU, MINGYAO, WANG, TAO, HE, LANGCHONG
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840669/
https://ncbi.nlm.nih.gov/pubmed/27168797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3172
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