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Reduced AMPKα2 protein expression restores glucose‐induced insulin secretion in islets from calorie‐restricted rats

In a state of caloric restriction (CR), improved insulin action was associated with the activation of AMP‐activated kinase (AMPK). Here, we verified whether AMPK was involved in impaired β‐cell function in islets from rats subjected to CR for 21 days. Eight‐week‐old male rats were distributed into a...

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Bibliografske podrobnosti
izdano v:Int J Exp Pathol
Main Authors: Amaral, Maria Esméria C., Ribeiro, Rosane A., Vanzela, Emerielle C., Barbosa‐Sampaio, Helena C.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840241/
https://ncbi.nlm.nih.gov/pubmed/27102713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12165
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