Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation

The glucagon-like peptide receptor (GLP-1R), which is a G-protein coupled receptor (GPCR), signals through both Gαs and Gαq coupled pathways and ERK phosphorylation to stimulate insulin secretion. The aim of this study was to determine molecular details of the effect of small molecule agonists, comp...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Thompson, Aiysha, Stephens, Jeffrey W., Bain, Stephen C., Kanamarlapudi, Venkateswarlu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839733/
https://ncbi.nlm.nih.gov/pubmed/27100083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154229
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items