M-Cells Contribute to the Entry of an Oral Vaccine but Are Not Essential for the Subsequent Induction of Protective Immunity against Francisella tularensis

M-cells (microfold cells) are thought to be a primary conduit of intestinal antigen trafficking. Using an established neutralizing anti-RANKL (Receptor Activator of NF-κB Ligand) antibody treatment to transiently deplete M-cells in vivo, we sought to determine whether intestinal M-cells were require...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cunningham, Aimee L., Guentzel, M. Neal, Yu, Jieh-Juen, Hung, Chiung-Yu, Forsthuber, Thomas G., Navara, Christopher S., Yagita, Hideo, Williams, Ifor R., Klose, Karl E., Eaves-Pyles, Tonyia D., Arulanandam, Bernard P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839702/
https://ncbi.nlm.nih.gov/pubmed/27100824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153402
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