Antigenic Fingerprinting following Primary RSV Infection in Young Children Identifies Novel Antigenic Sites and Reveals Unlinked Evolution of Human Antibody Repertoires to Fusion and Attachment Glycoproteins

Respiratory Syncytial Virus (RSV) is the major cause of pneumonia among infants. Here we elucidated the antibody repertoire following primary RSV infection and traced its evolution through adolescence and adulthood. Whole genome-fragment phage display libraries (GFPDL) expressing linear and conforma...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Fuentes, Sandra, Coyle, Elizabeth M., Beeler, Judy, Golding, Hana, Khurana, Surender
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839671/
https://ncbi.nlm.nih.gov/pubmed/27100289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005554
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