Novel Anthra[1,2-c][1,2,5]Thiadiazole-6,11-Diones as Promising Anticancer Lead Compounds: Biological Evaluation, Characterization & Molecular Targets Determination

The novel compounds NSC745885 and NSC757963 developed at our laboratory were tested against a panel of 60 cancer cell lines at the National Cancer Institute, USA, and a panel of 39 cancer cell lines at the Japanese Foundation of Cancer Research. Both compounds demonstrated selective unique multi-log...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ali, Ahmed Atef Ahmed, Lee, Yu-Ru, Chen, Tsung-Chih, Chen, Chun-Liang, Lee, Chia-Chung, Shiau, Chia-Yang, Chiang, Chiao-Hsi, Huang, Hsu-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839570/
https://ncbi.nlm.nih.gov/pubmed/27100886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154278
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