Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

Microbial cells embedded in a self-produced extracellular biofilm matrix cause chronic infections, e. g. by Pseudomonas aeruginosa in the lungs of cystic fibrosis patients. The antibiotic killing of bacteria in biofilms is generally known to be reduced by 100–1000 times relative to planktonic bacter...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Cao, Bao, Christophersen, Lars, Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus, Sams, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839563/
https://ncbi.nlm.nih.gov/pubmed/27100887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153616
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