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Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model

Microbial cells embedded in a self-produced extracellular biofilm matrix cause chronic infections, e. g. by Pseudomonas aeruginosa in the lungs of cystic fibrosis patients. The antibiotic killing of bacteria in biofilms is generally known to be reduced by 100–1000 times relative to planktonic bacter...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Cao, Bao, Christophersen, Lars, Kolpen, Mette, Jensen, Peter Østrup, Sneppen, Kim, Høiby, Niels, Moser, Claus, Sams, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839563/
https://ncbi.nlm.nih.gov/pubmed/27100887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153616
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