Stability and Loss of a Virus Resistance Phenotype Over Time in Transgenic Mosquitoes harboring an antiviral effector gene

Transgenic Aedes aegypti were engineered to express a virus-derived, inverted repeat (IR) RNA in the mosquito midgut to trigger RNA interference (RNAi) and generate resistance to dengue virus type 2 (DENV2) in the vector. Here we characterize genotypic and phenotypic stabilities of one line, Carb77,...

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Bibliografske podrobnosti
izdano v:Insect Mol Biol
Main Authors: Franz, Alexander W.E., Sanchez-Vargas, Irma, Piper, Joseph, Smith, Mark R., James, Anthony A., Olson, Ken E.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839482/
https://ncbi.nlm.nih.gov/pubmed/19754743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2583.2009.00908.x
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