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Commentary: IL-12-secreting tumor-targeted chimeric antigen receptor T cells: An unaddressed concern on Koneru et al. (2015)

To date, chimeric antigen receptor (CAR) T cells have shown remarkable responses in patients with certain hematological malignancies particularly acute lymphocytic leukemia (ALL), but have led to more limited success with solid tumors probably due to immunosuppressive networks in the tumor environme...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Mirzaei, Hamid Reza, Hadjati, Jamshid
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839381/
https://ncbi.nlm.nih.gov/pubmed/27141362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1100792
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