Antitumor cytotoxicity induced by bone-marrow-derived antigen-presenting cells is facilitated by the tumor suppressor protein p53 via regulation of IL-12

Activated antigen-presenting cells (APC) deliver the three signals cytotoxic T cells require to differentiate into effector cells that destroy the tumor. These comprise antigen, co-stimulatory signals and cytokines. Once these cells have carried out their function, they apoptose. We hypothesized tha...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncoimmunology
Egile Nagusiak: Slatter, Tania L., Wilson, Michelle, Tang, Chingwen, Campbell, Hamish G., Ward, Vernon K., Young, Vivienne L., Van Ly, David, Fleming, Nicholas I., Braithwaite, Antony W., Baird, Margaret A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839352/
https://ncbi.nlm.nih.gov/pubmed/27141366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1112941
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