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Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?

Pancreatic cancer is extremely resistant to chemo- and radiation-therapies due to its inherent genetic instability, the local immunosuppressive microenvironment and the remarkable desmoplastic stromal changes which characterize this cancer. Therefore, there is an urgent need for improvement on stand...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Brunet, Laura Rosa, Hagemann, Thorsten, Gaya, Andrew, Mudan, Satvinder, Marabelle, Aurelien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839322/
https://ncbi.nlm.nih.gov/pubmed/27141395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1112942
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