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Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?

Pancreatic cancer is extremely resistant to chemo- and radiation-therapies due to its inherent genetic instability, the local immunosuppressive microenvironment and the remarkable desmoplastic stromal changes which characterize this cancer. Therefore, there is an urgent need for improvement on stand...

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Podrobná bibliografie
Vydáno v:Oncoimmunology
Hlavní autoři: Brunet, Laura Rosa, Hagemann, Thorsten, Gaya, Andrew, Mudan, Satvinder, Marabelle, Aurelien
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839322/
https://ncbi.nlm.nih.gov/pubmed/27141395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1112942
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