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Have lessons from past failures brought us closer to the success of immunotherapy in metastatic pancreatic cancer?

Pancreatic cancer is extremely resistant to chemo- and radiation-therapies due to its inherent genetic instability, the local immunosuppressive microenvironment and the remarkable desmoplastic stromal changes which characterize this cancer. Therefore, there is an urgent need for improvement on stand...

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Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: Brunet, Laura Rosa, Hagemann, Thorsten, Gaya, Andrew, Mudan, Satvinder, Marabelle, Aurelien
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839322/
https://ncbi.nlm.nih.gov/pubmed/27141395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1112942
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