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Metabolic tug-of-war in tumors results in diminished T cell antitumor immunity

Glycolytic activity in T cells governs T cell responses by controlling various cellular processes, including proliferation, survival, and effector functions. We recently showed that the tumor microenvironment diminishes T cell antitumor responses by depriving glucose to infiltrating T cells. Moreove...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Cheng, Wan-Chen, Ho, Ping-Chih
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839318/
https://ncbi.nlm.nih.gov/pubmed/27141402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1119355
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