Environmental Correlation Analysis for Genes Associated with Protection against Malaria

Genome-wide searches for loci involved in human resistance to malaria are currently being conducted on a large scale in Africa using case-control studies. Here, we explore the utility of an alternative approach—“environmental correlation analysis, ECA,” which tests for clines in allele frequencies a...

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Veröffentlicht in:Mol Biol Evol
Hauptverfasser: Mackinnon, Margaret J., Ndila, Carolyne, Uyoga, Sophie, Macharia, Alex, Snow, Robert W., Band, Gavin, Rautanen, Anna, Rockett, Kirk A., Kwiatkowski, Dominic P., Williams, Thomas N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Discoveries
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839215/
https://ncbi.nlm.nih.gov/pubmed/26744416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw004
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