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Polo Kinase Phosphorylates Miro to Control ER-Mitochondria Contact Sites and Mitochondrial Ca(2+) Homeostasis in Neural Stem Cell Development
Mitochondria play central roles in buffering intracellular Ca(2+) transients. While basal mitochondrial Ca(2+) (Ca(2+)(mito)) is needed to maintain organellar physiology, Ca(2+)(mito) overload can lead to cell death. How Ca(2+)(mito) homeostasis is regulated is not well understood. Here we show that...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839004/ https://ncbi.nlm.nih.gov/pubmed/27093086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.03.023 |
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