NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction

Indian Echis carinatus bite causes sustained tissue destruction at the bite site. Neutrophils, the major leukocytes in the early defence process, accumulate at the bite site. Here we show that E. carinatus venom induces neutrophil extracellular trap (NET) formation. The NETs block the blood vessels...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Katkar, Gajanan D., Sundaram, Mahalingam S., NaveenKumar, Somanathapura K., Swethakumar, Basavarajaiah, Sharma, Rachana D., Paul, Manoj, Vishalakshi, Gopalapura J., Devaraja, Sannaningaiah, Girish, Kesturu S., Kemparaju, Kempaiah
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838891/
https://ncbi.nlm.nih.gov/pubmed/27093631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11361
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