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Free fatty acid palmitate activates unfolded protein response pathway and promotes apoptosis in meniscus cells

INTRODUCTION: Obesity is the major risk factor for the development of osteoarthritis (OA); however, the mechanisms involved are not clearly understood. Obesity is associated with increased production of adipokine and elevated levels of circulating free fatty acids (FFA). A recent study has shown tha...

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Detalhes bibliográficos
Publicado no:Osteoarthritis Cartilage
Main Authors: Haywood, Jamie, Yammani, Raghunatha R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838514/
https://ncbi.nlm.nih.gov/pubmed/26687823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.11.020
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