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Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-Staphylococcal activity

The continuous rise of multi-drug resistant pathogenic bacteria has become a significant challenge for the health care system. In particular, novel drugs to treat infections of methicillin-resistant Staphylococcus aureus strains (MRSA) are needed, but traditional drug discovery campaigns have largel...

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Bibliografske podrobnosti
izdano v:Metallomics
Main Authors: Dalecki, Alex G., Malalasekera, Aruni P., Schaaf, Kaitlyn, Kutsch, Olaf, Bossmann, Stefan H., Wolschendorf, Frank
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838501/
https://ncbi.nlm.nih.gov/pubmed/26935206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mt00003g
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