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Novel Antioxidants Protect Mitochondria from the Effects of Oligomeric Amyloid Beta and Contribute to the Maintenance of Epigenome Function

Alzheimer’s disease is associated with metabolic deficits and reduced mitochondrial function, with the latter due to the effects of oligomeric amyloid beta peptide (AβO) on the respiratory chain. Recent evidence has demonstrated reduction of epigenetic markers, such as DNA methylation, in Alzheimer’...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Mastroeni, Diego, Khdour, Omar M., Arce, Pablo M., Hecht, Sidney M., Coleman, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838453/
https://ncbi.nlm.nih.gov/pubmed/25668062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500323q
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