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A Strategy for Suppressing Redox Stress within Mitochondria
[Image: see text] An aza analogue (1) of the experimental neuroprotective drug idebenone has been prepared and evaluated. The compound quenches lipid peroxidation more effectively than α-tocopherol and potently suppresses reactive oxygen species in cells under oxidative stress. It is thought to do s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2011
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018135/ https://ncbi.nlm.nih.gov/pubmed/24900356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200095w |
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