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Detrimental effects of adenosine signaling in sickle cell disease

Hypoxia can act as an initial trigger to induce erythrocyte sickling and eventual end organ damage in sickle cell disease (SCD). Many factors and metabolites are altered in response to hypoxia and may contribute to the pathogenesis of the disease. Using metabolomic profiling, we found that the stead...

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書目詳細資料
發表在:Nat Med
Main Authors: Zhang, Yujin, Dai, Yingbo, Wen, Jiaming, Zhang, Weiru, Grenz, Almut, Sun, Hong, Tao, Lijian, Lu, Guangxiu, Alexander, Danny C, Milburn, Michael V, Carter-Dawson, Louvenia, Lewis, Dorothy E, Zhang, Wenzheng, Eltzschig, Holger K, Kellems, Rodney E, Blackburn, Michael R, Juneja, Harinder S, Xia, Yang
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838392/
https://ncbi.nlm.nih.gov/pubmed/21170046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2280
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