Augmentation of CFTR maturation by S-nitrosoglutathione reductase

S-nitrosoglutathione (GSNO) reductase regulates novel endogenous S-nitrosothiol signaling pathways, and mice deficient in GSNO reductase are protected from airways hyperreactivity. S-nitrosothiols are present in the airway, and patients with cystic fibrosis (CF) tend to have low S-nitrosothiol level...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Zaman, Khalequz, Sawczak, Victoria, Zaidi, Atiya, Butler, Maya, Bennett, Deric, Getsy, Paulina, Zeinomar, Maryam, Greenberg, Zivi, Forbes, Michael, Rehman, Shagufta, Jyothikumar, Vinod, DeRonde, Kim, Sattar, Abdus, Smith, Laura, Corey, Deborah, Straub, Adam, Sun, Fei, Palmer, Lisa, Periasamy, Ammasi, Randell, Scott, Kelley, Thomas J., Lewis, Stephen J., Gaston, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838141/
https://ncbi.nlm.nih.gov/pubmed/26637637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00269.2014
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