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Low Prolactin and High 20-α-Hydroxysteroid Dehydrogenase Levels Contribute to Lower Progesterone Levels in HIV-Infected Pregnant Women Exposed to Protease Inhibitor–Based Combination Antiretroviral Therapy

Background. It has been reported that pregnant women receiving protease inhibitor (PI)–based combination antiretroviral therapy (cART) have lower levels of progesterone, which put them at risk of adverse birth outcomes, such as low birth weight. We sought to understand the mechanisms involved in thi...

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Vydáno v:J Infect Dis
Hlavní autoři: Papp, Eszter, Balogun, Kayode, Banko, Nicole, Mohammadi, Hakimeh, Loutfy, Mona, Yudin, Mark H., Shah, Rajiv, MacGillivray, Jay, Murphy, Kellie E., Walmsley, Sharon L., Silverman, Michael, Serghides, Lena
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837912/
https://ncbi.nlm.nih.gov/pubmed/26740274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw004
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