α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals

α-Synuclein (α-syn) missense and multiplication mutations have been suggested to cause neurodegenerative diseases, including Parkinson's disease (PD) and dementia with Lewy bodies. Before causing the progressive neuronal loss, α-syn mutations impair exocytosis, which may contribute to eventual...

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Udgivet i:J Neurosci
Main Authors: Xu, Jianhua, Wu, Xin-Sheng, Sheng, Jiansong, Zhang, Zhen, Yue, Hai-Yuan, Sun, Lixin, Sgobio, Carmelo, Lin, Xian, Peng, Shiyong, Jin, Yinghui, Gan, Lin, Cai, Huaibin, Wu, Ling-Gang
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837680/
https://ncbi.nlm.nih.gov/pubmed/27098685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3627-15.2016
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