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Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines
AIM: To study the effect of anti-copper treatment for survival of hepatic cells expressing different ATP7B mutations in cell culture. METHODS: The most common Wilson disease (WD) mutations p.H1069Q, p.R778L and p.C271*, found in the ATP7B gene encoding a liver copper transporter, were studied. The m...
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| Publicado en: | World J Gastroenterol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Baishideng Publishing Group Inc
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837429/ https://ncbi.nlm.nih.gov/pubmed/27122662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i16.4109 |
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