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A somatic reference standard for cancer genome sequencing

Large-scale multiplexed identification of somatic alterations in cancer has become feasible with next generation sequencing (NGS). However, calibration of NGS somatic analysis tools has been hampered by a lack of tumor/normal reference standards. We thus performed paired PCR-free whole genome sequen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Craig, David W., Nasser, Sara, Corbett, Richard, Chan, Simon K., Murray, Lisa, Legendre, Christophe, Tembe, Waibhav, Adkins, Jonathan, Kim, Nancy, Wong, Shukmei, Baker, Angela, Enriquez, Daniel, Pond, Stephanie, Pleasance, Erin, Mungall, Andrew J., Moore, Richard A., McDaniel, Timothy, Ma, Yussanne, Jones, Steven J. M., Marra, Marco A., Carpten, John D., Liang, Winnie S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837349/
https://ncbi.nlm.nih.gov/pubmed/27094764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24607
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