A somatic reference standard for cancer genome sequencing

Large-scale multiplexed identification of somatic alterations in cancer has become feasible with next generation sequencing (NGS). However, calibration of NGS somatic analysis tools has been hampered by a lack of tumor/normal reference standards. We thus performed paired PCR-free whole genome sequen...

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Pubblicato in:Sci Rep
Autori principali: Craig, David W., Nasser, Sara, Corbett, Richard, Chan, Simon K., Murray, Lisa, Legendre, Christophe, Tembe, Waibhav, Adkins, Jonathan, Kim, Nancy, Wong, Shukmei, Baker, Angela, Enriquez, Daniel, Pond, Stephanie, Pleasance, Erin, Mungall, Andrew J., Moore, Richard A., McDaniel, Timothy, Ma, Yussanne, Jones, Steven J. M., Marra, Marco A., Carpten, John D., Liang, Winnie S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837349/
https://ncbi.nlm.nih.gov/pubmed/27094764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24607
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