Ha-ras oncogene activation in mammary glands of N-methyl-N-nitrosourea-treated rats genetically resistant to mammary adenocarcinogenesis.

A single dose of N-methyl-N-nitrosourea given to sexually immature female Buf/N rats produces a high incidence of mammary adenocarcinomas. A large percentage of these tumors contain the Ha-ras oncogene, activated by a G----A transition at the second nucleotide of codon 12. Copenhagen rats, on the ot...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lu, S J, Archer, M C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1736280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.3.1001
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