Ha-ras oncogene activation in mammary glands of N-methyl-N-nitrosourea-treated rats genetically resistant to mammary adenocarcinogenesis.
A single dose of N-methyl-N-nitrosourea given to sexually immature female Buf/N rats produces a high incidence of mammary adenocarcinomas. A large percentage of these tumors contain the Ha-ras oncogene, activated by a G----A transition at the second nucleotide of codon 12. Copenhagen rats, on the ot...
Sparad:
| I publikationen: | Proc Natl Acad Sci U S A |
|---|---|
| Huvudupphov: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
National Academy of Sciences
1992
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1736280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.3.1001 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|