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miR-186 is decreased in aged brain and suppresses BACE1 expression

Accumulation of amyloid β (Aβ) in the brain is a key pathological hallmark of Alzheimer’s disease (AD). Because aging is the most prominent risk factor for AD, understanding the molecular changes during aging is likely to provide critical insights into AD pathogenesis. However, studies on the role o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neurochem
Main Authors: Kim, Jaekwang, Yoon, Hyejin, Chung, Dah-eun, Brown, Jennifer L., Belmonte, Krystal C., Kim, Jungsu
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837067/
https://ncbi.nlm.nih.gov/pubmed/26710318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13507
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