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miR-186 is decreased in aged brain and suppresses BACE1 expression
Accumulation of amyloid β (Aβ) in the brain is a key pathological hallmark of Alzheimer’s disease (AD). Because aging is the most prominent risk factor for AD, understanding the molecular changes during aging is likely to provide critical insights into AD pathogenesis. However, studies on the role o...
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| Udgivet i: | J Neurochem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837067/ https://ncbi.nlm.nih.gov/pubmed/26710318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13507 |
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