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Protein phosphatase 2A is requisite for the function of regulatory T cells

Immune homeostasis depends on the proper function of regulatory T (T(reg)) cells. Compromised T(reg) cell suppressive activity leads to autoimmune disease, graft rejection and promotes anti-tumor immunity. Here we report the previously unrecognized requirement of the serine/threonine phosphatase Pro...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Apostolidis, Sokratis A., Rodríguez-Rodríguez, Noé, Suárez-Fueyo, Abel, Dioufa, Nikolina, Ozcan, Esra, Crispín, José C., Tsokos, Maria G., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837024/
https://ncbi.nlm.nih.gov/pubmed/26974206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3390
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