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Quantitative Proteomics Identifies Serum Response Factor Binding Protein 1 as a Host Factor for Hepatitis C Virus Entry

Hepatitis C virus (HCV) enters human hepatocytes through a multistep mechanism involving, among other host proteins, the virus receptor CD81. How CD81 governs HCV entry is poorly characterized, and CD81 protein interactions after virus binding remain elusive. We have developed a quantitative proteom...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Gerold, Gisa, Meissner, Felix, Bruening, Janina, Welsch, Kathrin, Perin, Paula M., Baumert, Thomas F., Vondran, Florian W., Kaderali, Lars, Marcotrigiano, Joseph, Khan, Abdul G., Mann, Matthias, Rice, Charles M., Pietschmann, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Authors. Published by Elsevier Inc. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836839/
https://ncbi.nlm.nih.gov/pubmed/26212323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.063
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