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G-Protein–Coupled Receptors Signaling Pathways in New Antiplatelet Drug Development

Platelet G-protein–coupled receptors influence platelet function by mediating the response to various agonists, including ADP, thromboxane A(2), and thrombin. Blockade of the ADP receptor, P2Y(12), in combination with cyclooxygenase-1 inhibition by aspirin has been among the most widely used pharmac...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Gurbel, Paul A., Kuliopulos, Athan, Tantry, Udaya S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836833/
https://ncbi.nlm.nih.gov/pubmed/25633316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.303412
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