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Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix

Triple-stranded RNA was first deduced to form in vitro more than 50 years ago and has since been implicated in RNA catalysis, stability, and small molecule binding. Despite the emerging biological significance of RNA triple helices, it remains unclear how their nucleotide composition contributes to...

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Detalles Bibliográficos
Publicado en:RNA
Main Authors: Brown, Jessica A., Kinzig, Charles G., DeGregorio, Suzanne J., Steitz, Joan A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836648/
https://ncbi.nlm.nih.gov/pubmed/26952103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055707.115
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