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The deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping
Decay of mRNA is essential for the efficient regulation of gene expression. A major pathway of mRNA degradation is initiated by the shortening of the poly(A) tail via the CCR4/NOT deadenylase complex. Deadenylation is followed by removal of the 5′ cap (i.e., decapping) and then 5′ to 3′ exonucleolyt...
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| Veröffentlicht in: | RNA |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836645/ https://ncbi.nlm.nih.gov/pubmed/26952104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.054742.115 |
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